experimental allergic encephalomyelitis
- experimental allergic encephalomyelitis
-
An
autoimmune disease that can be induced in various experimental animals by the injection of homogenized brain or
spinal cord in Freund\'s adjuvant. The
antigen appears to be
a basic
protein present in myelin, and the response is characterized by focal areas of
lymphocyte and
macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Sometimes used as
a model for demyelinating diseases, although whether this is entirely justifiable is not clear.
Dictionary of molecular biology.
2004.
Look at other dictionaries:
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